Biopharmaceutical companies today are challenged to develop high producing cell lines as quickly as possible. Commercially available media may fall short of performance expectations required to meet targets. The alternative —fully customized media and feed development — requires significant funding, time and in-house expertise in media development.
In life science, biopharma and other areas of research, development and production, design of experiments (DOE) provides a systematic method to determine cause and effect relationships between factors and responses affecting a process, product or analytical system. But the key to understanding your results is effective analysis of your experimental data.
Principal component analysis, or PCA, is a statistical procedure that allows you to summarize the information content in large data tables by means of a smaller set of “summary indices” that can be more easily visualized and analyzed. The underlying data can be measurements describing properties of production samples, chemical compounds or reactions, process time points of a continuous process, batches from a batch process, biological individuals or trials of a DOE-protocol, for example.
How Multivariate Data Analysis Can Separate the Players from the Gorillas
We have more data than ever before coming at us from many sources – both in our personal lives as well as business. Data is everywhere: from the production flow of a manufacturing floor to the sales results in a grocery store to the number of shares a page gets on Facebook. How do you sort it all out in a way that makes sense? Which data should you worry about and which should you ignore?