A team at Glaxo Smith Kline, GSK, has carried out several studies using Raman spectroscopy and multivariate data analytics in order to monitor upstream cell culture processes. The studies show that Raman spectroscopy is a valuable analytical tool for enabling real-time monitoring and control of production bioreactors and that improved control can lead to improved product quality. Below is a summary of the studies.
An important step on the road to creating treatments for illnesses like COVID-19, which has caused the recent global pandemic, may start with understanding the similarities and differences between the various strains of coronavirus known to exist today. Making sense of large and complex sets of data, especially those that require novel interpretation, calls for a powerful analytics toolset to speed up the process.
Out of control processes in pharma manufacturing are not something to take lightly. If your production runs are seeing frequent deviations, leading to expensive batch losses or frequent rework, it’s time to take a look at ways to correct any process deviations in a more expedient manner. Uncorrected deviations or processes that vary from approved process parameters can lead to costly and dangerous mistakes.