Umetrics Suite Blog

Using data analytics to optimize design space and setpoint conditions for bioreactors

May 18, 2018

At the heart of any process used to manufacture biological products is a bioreactor setup that supports a stable and reproducible biologically active environment. The bioreactor provides a controlled environment to achieve optimal growth for the particular cell cultures being used.

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How to optimize cell culture media to speed biopharma development

May 7, 2018

Biopharmaceutical companies today are challenged to develop high producing cell lines as quickly as possible. Commercially available media may fall short of performance expectations required to meet targets. The alternative —fully customized media and feed development — requires significant funding, time and in-house expertise in media development.

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What tools make DOE data analysis faster and more accurate?

April 19, 2018

In life science, biopharma and other areas of research, development and production, design of experiments (DOE) provides a systematic method to determine cause and effect relationships between factors and responses affecting a process, product or analytical system. But the key to understanding your results is effective analysis of your experimental data.

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Identifying ways to make biomass a more effective alternative energy source

December 19, 2017

Worldwide demand for energy escalates every year, and the consumption of fossil fuels continues to increase despite the growing supply of alternative energy options. Globally, about 81 percent of energy comes from a finite supply of fossil fuels like oil, coal and natural gas. Fossil fuels are used to heat homes, run vehicles, power industry and manufacturing, and provide electricity.

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Creating a design of experiments study to predict formula robustness

November 9, 2017

Using a Quality by Design (QbD) approach for DOE supports ICH Q8 compliance

In pharmaceutical development, manufacturers must be able to demonstrate product robustness and deliver the intended quality of the product within allowable ranges for the claimed shelf-life period. Both international and country specific regulatory agencies, such as the FDA, pay close attention to these claims.

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What is DOE? Design of Experiments Basics for Beginners

September 21, 2017

Whether you work in engineering, R&D, or a science lab, understanding the basics of experimental design can help you achieve more statistically optimal results from your experiments or improve your output quality.

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