In this blog post, we’ll take a closer look at a feature of the SIMCA data analytics software called the Omics skin. So what exactly is an “omics” skin?
In chemical manufacturing, the process involved in creating a breakthrough new solvent or substance often takes years, or even decades, with ongoing tests that may be based on trial and error as much as specifically applied knowledge. One area of development that is particularly important in the chemical industry is creating new substances called plasticizers that can help resins or polymers retain a more supple or flexible nature.
In this blog post we will take a closer look at OPLS*, or Orthogonal PLS, a method to model process data. The advantage of OPLS compared to PLS is that you can uncover hidden details and get a more precise understanding of your data – all of which will help you build better predictive models of your processes.
Worldwide demand for energy escalates every year, and the consumption of fossil fuels continues to increase despite the growing supply of alternative energy options. Globally, about 81 percent of energy comes from a finite supply of fossil fuels like oil, coal and natural gas. Fossil fuels are used to heat homes, run vehicles, power industry and manufacturing, and provide electricity.
All manufacturing industries need good control and good overview of their production processes. As already discussed in a previous blog post, SIMCA-online enables you to apply advanced multivariate data analytics in real time to monitor your production processes, for example to make sure that your production process is behaving as it should or that the quality is what it should be.
In manufacturing and other industries that have complex processes, knowing which variables have the most impact on quality and at what point, or knowing which combination of variables to change in order to improve your process, can have a huge impact on the overall quality or profitability of your manufacturing process. But without making expensive and time-consuming changes in the physical processes in order to test all possible scenarios, how can you identify and predict the variables that have the most significant impact on your outputs?
Using real-time data analytics monitoring has become the accepted way to monitor processes in several industries. The goal is to detect and diagnose issues as they happen, which is a great leap forward compared to traditional analysis conducted in retrospect. This has been highlighted in a previous blog post.
In a previous blog post we discussed how SIMCA-online can help you make complex data simple and ensure that you get maximum value from your data.
In this blog post we will introduce a number of benefits of the newly released versions of SIMCA 15 and SIMCA-online 15. To mention just a few things, you get a much improved ability to model and control complete processes, including processes with a very high complexity. You also get a much better connection between SIMCA and SIMCA-online so that information can flow in both ways.
An important environmental issue that has come into focus is the increasing number of chemicals that we are exposed to in our everyday life. Chemicals are found in products ranging from cars and furniture to clothing and skincare, and are also by-products from combustion. The CAS REGISTRYSM, an international standard for chemical information, currently contains more than 134 million unique organic and inorganic chemical substances and more than 67 million sequences.
Using a Quality by Design (QbD) approach for DOE supports ICH Q8 compliance
In pharmaceutical development, manufacturers must be able to demonstrate product robustness and deliver the intended quality of the product within allowable ranges for the claimed shelf-life period. Both international and country specific regulatory agencies, such as the FDA, pay close attention to these claims.